Catalog No. : SER-0710-0207

Seraseq™ ctDNA Reference Material v2 AF 0.125%

Seraseq™ ctDNA Reference Material v2 AF 0.125%


To overcome the lack of patient-like reference materials for liquid biopsy, including drawbacks of existing methodologies such as sonication, SeraCare has developed a breakthrough technology that produces the most patient-like materials compared to native ctDNA. The Seraseq ctDNA Mutation Mix v2 is a highly multiplexed product for NGS-based ctDNA assays targeting cancer-relevant somatic mutations.

This specific ctDNA Reference Material v2 product has an allele frequency of 0.125%.

  • Size distribution, library yield and complexity consistent with native ctDNA
  • Single sample with 40 clinically-relevant mutations across 28 genes, all at the same specified allele frequency
  • Offered in a full-process plasma-like material capable of assessing the entire workflow from extraction through analysis
  • Mutation targets precisely quantitated with digital PCR
  • Single well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured in GMP-compliant and ISO 13485-certified facilities
ItemSize Application Price
Seraseq™ ctDNA Reference Material v2 AF 0.125%

1 X 5mL

Next Gen Sequencing $886.00

# of variants
Allele Frequency
Fragment Size
170bp average (and encapsulated)
25 ng/µL 
125 ng (single vial)
SeraCon™ Matribase (human plasma-like matrix)

Related Products

ItemSizeMakeCatalog No.ApplicationPriceQty
Seraseq™ ctDNA Reference Material v2 WT

1 X 5mL

SeraCare SER-0710-0208 Next Gen Sequencing
ItemSizeMakeCatalog No.ApplicationPriceQty
Seraseq™ ctDNA Complete™ Reference Material AF 0.1%

1 x 25 µL

SeraCare SER-0710-0673 Next Gen Sequencing