Catalog No. : COV-500506

ME220 Focused-ultrasonicator

ME220 Focused-ultrasonicator


1 to 8 sample batch processing at the bench-top

  • The “Scientist’s Standard” in a compact, easy-to-use system, formatted for batch-processing
  • Precise and accurate results with AFA-energetics
  • Integrated chiller and automated water management
  • Powerful SonoLab software with pre-loaded protocols
  • Less than 2 minute start-up time
  • The automated water management system provides a 30-day run capacity, making it virtually maintenance-free.

The ME220 Focused-ultrasonicator is the multi-sample, multi-application benchtop sample preparation solution for every lab.

Single Box Design

  • Automated water maintenance
  • 30-day run capacity

Focused-ultrasonicator Assembly

  • 8 microTUBE strip and rack
  • AFA multi-sample acoustic module
  • Low-volume waterbath

Highly Accurate Control

  • Real-time monitoring and integrated Quality Control with SonoLab software
  • Integrated engineered design
  • Custom Class D, high-efficiency electronics
  • Calibrated to NIST traceable standards

Optimized Pre-diagnostic Applications:

Mechanical Shearing for Next Generation Sequencing (NGS)

Enable Precision Medicine with Clinical-grade Nucleic Acid Preparation

DNA/RNA Extraction from Formalin-Fixed, Paraffin-Embedded (FFPE) Tissue Samples

NGS-grade DNA and RNA from FFPE Tissue

DNA Extraction from Dried Blood Spots (DBS)

Extract NGS-grade DNA from Standard Card Punches

Extract DNA for NGS from Whole Blood

Collect, Dry-stabilize, Transport, and Extract with truCOLLECT

Chromatin Mechanical Shearing for ChIP-Seq

Improve Reproducibility, Increase Sensitivity, Obtain Unbiased Results

Biomarker Extraction for Research and Clinical Microbiology

Extract, Sequence, Identify, and Characterize

Key Features:

Isothermal process

No heat-induced bias, high sample recovery

Small, compact footprint

Fits on any bench top

Non-contact, closed vessel

No cross-contamination, aerosols, or clean-up

Flexible sample processing volume

15 μl to 1 ml

Highly reproducible results

Minimal post-process QC required


Sample vessels compatible with liquid handling robots

Sample tracking with 2D barcoded consumables

Traceable sample identification

Operates at 500 kHz (Ultrasonic Range)

Beyond audible range – no discomfort to operators

Calibrated to NIST traceable standards

Optimized protocols available and transferable

ItemSize Application Price
ME220 Focused-ultrasonicator

1 Unit

Shearing Next Gen Sequencing Automation Please Inquire


Focused-ultrasonicator – 1 to 8 sample batch process

Included: dedicated notebook computer, SonoLab™ software, integrated chiller, and automated water bath control

Part Number
PN 500506
Treatment Power

75 Watts Peak Power

20 Watts Average Incident Power

18.75” W x 18.75” D x 14.75”H (47.75 cm x 47.75 cm x 37.5 cm)
Approximately 40 lbs (19.1 kg)
Power Requirements
100-240 VAC 500 VA, 50-60Hz, 5 Amp Slo-Blow Fuse
Operating Environment

Ambient temperature:  19°C to 25°C  (66°F to 77°C)

Relative humidity:  30% to 70%

Regulatory Labeling
CE, ETL Mark (for Product Safety), WEEE
Certified to IEC/EN/ANSI/UL61010-1 and CAN/CSA C22.2 No. 61060-1 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part 1: General Requirements”
Water Bath
AFA-grade Water (Covaris PN 520101 or Highly Purified Water at least ASTM Type III or ISO grade 3)
Method Temperature Set Point
Programmable +6.0° C to +40.0° C
Certified to EN 61326-1 “Electrical equipment for measurement, control and laboratory use – EMC requirements – Part 1: General requirements”.  Also certified to FCC 47CFR Part 15 – Radio Frequency Devices and Part 18 – Industrial, Scientific and Medical Equipment, and ICES-003 Class A for Industry Canada
Operating System
Microsoft Windows 7 or Higher
Data Input
Keyboard, Touchpad
Integrated Cooling Power
Solid state chiller for heating and cooling (built in) 0 – 160 Watts, 24 volts


ME220 operation and setup

Please Inquire